Jobs / Healthcare / 29-2011.04

Histotechnologists

Apply knowledge of health and disease causes to evaluate new laboratory techniques and procedures to examine tissue samples. Process and prepare histological slides from tissue sections for microscopic examination and diagnosis by pathologists. May solve technical or instrument problems or assist with research studies.

US jobs
Not reported by BLS
Job family
Healthcare

Can agents do the work of histotechnologists?

We read the evidence at the level of the job family, Healthcare:

  • Task levelPartialOne benchmark, from early 2025. On Stanford's MedAgentBench, where agents do clinical tasks in a simulated electronic health record, the best recorded model completes 69.7% of tasks (Claude 3.5 Sonnet v2). It has no maintained leaderboard, so newer models are not measured. No benchmark in our collection tests work with patients.
  • Project levelPartialOnly adjacent evidence. GDPval includes nurses among its 44 occupations. OpenAI reports that GPT-5.5's deliverables won or tied against professionals' work in 84.9% of comparisons across all occupations. No benchmark in our collection tests clinical work over days, such as managing a patient's care.

Benchmarks for the job family

These cover work in healthcare, not always this occupation's tasks.

  • GDPvalby OpenAIProject level · Wins plus ties against experts
    84.9%GPT-5.5 · Apr 2026
    Strong
  • GDPval-AAby Artificial AnalysisProject level · GDPval-AA Elo
    1846 EloClaude Opus 5.5 (Adaptive Reasoning, Max Effort, Default Fallback) · 23 Sep 2026
    Unrated
  • MedAgentBenchby Stanford UniversityTask level · Task success rate
    69.7%Claude 3.5 Sonnet v2 · 24 Jan 2025
    Strong

Typical tasks

From O*NET 31.0. Core tasks first. Few of these tasks have a benchmark today.

  • Embed tissue specimens into paraffin wax blocks, or infiltrate tissue specimens with wax.
  • Cut sections of body tissues for microscopic examination, using microtomes.
  • Stain tissue specimens with dyes or other chemicals to make cell details visible under microscopes.
  • Compile materials for distribution to pathologists, such as surgical working drafts, requisitions, and slides.
  • Compile and maintain records of preventive maintenance and instrument performance checks according to schedule and regulations.
  • Perform tests by following physician instructions.
  • Operate computerized laboratory equipment to dehydrate, decalcify, or microincinerate tissue samples.
  • Prepare substances, such as reagents and dilution, and stains for histological specimens according to protocols.
  • Resolve problems with laboratory equipment and instruments, such as microscopes, mass spectrometers, microtomes, immunostainers, tissue processors, embedding centers, and water baths.
  • Examine slides under microscopes to ensure tissue preparation meets laboratory requirements.
  • Prepare or use prepared tissue specimens for teaching, research or diagnostic purposes.
  • Perform procedures associated with histochemistry to prepare specimens for immunofluorescence or microscopy.
Other job titles for this occupation (10)

Clinical Lab Manager (Clinical Laboratory Manager) · Histology Lab Manager (Histology Laboratory Manager) · Histology Specialist · Histology Technologist · Histotechnologist · Grossing Technician (Grossing Tech) · Histocompatibility Technologist · Histologist · Histotechnician · Mohs Technician (Micrographically Oriented Histographic Surgery Technician)